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antibodies against pax2  (Santa Cruz Biotechnology)


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    Santa Cruz Biotechnology antibodies against pax2
    OVE clonal cells have different cell morphology and gene expressions. ( A ) Microphotographs of OVE clonal cells show the epithelial morphology of BRCA1-C2-flox cells and the more mesenchymal morphology of the other three cell lines. Scale bar: 100 μm. ( B ) qPCR analysis shows variable gene expression for epithelial markers ( Cdh1 and Krt19 ), tumor suppressor genes ( Trp53 and Brca1 ), and OVE markers ( Ovgp1, Foxj1, <t>Pax2,</t> and Pax8 ) among the four cell lines. In line with their morphology, BRCA1-C2-flox clonal cells express higher levels of transcripts for epithelial markers ( Cdh1 and Krt19 ) and markers of ciliated cells ( Foxj1 ) relative to most of the other cell lines. P53-flox and P53/BRCA1-flox cells express lower levels of mRNA for epithelial markers ( Cdh1 and Krt19 ) and elevated levels of secretory cell markers ( Ovgp1 ). Pax8 mRNA is equally expressed in all OVE clonal cells, whereas Pax2 is highly expressed in the BRCA1-C1-flox cells. Analyses were performed using multiple t -test analyses for three independent experiments. * p < 0.01, ** p < 0.001, and **** p < 0.00001.
    Antibodies Against Pax2, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 49 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/pax+2/Pax-2+Antibody/pmc12564701-90-9-14
    Average 93 stars, based on 49 article reviews
    antibodies against pax2 - by Bioz Stars, 2026-08
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    Images

    1) Product Images from "P53 Mutation Induces Epithelial-to-Mesenchymal Transition (EMT) Associated with Stem Cell Properties and Tumorigenesis in Fallopian Tube Cells"

    Article Title: P53 Mutation Induces Epithelial-to-Mesenchymal Transition (EMT) Associated with Stem Cell Properties and Tumorigenesis in Fallopian Tube Cells

    Journal: Cancers

    doi: 10.3390/cancers17203317

    OVE clonal cells have different cell morphology and gene expressions. ( A ) Microphotographs of OVE clonal cells show the epithelial morphology of BRCA1-C2-flox cells and the more mesenchymal morphology of the other three cell lines. Scale bar: 100 μm. ( B ) qPCR analysis shows variable gene expression for epithelial markers ( Cdh1 and Krt19 ), tumor suppressor genes ( Trp53 and Brca1 ), and OVE markers ( Ovgp1, Foxj1, Pax2, and Pax8 ) among the four cell lines. In line with their morphology, BRCA1-C2-flox clonal cells express higher levels of transcripts for epithelial markers ( Cdh1 and Krt19 ) and markers of ciliated cells ( Foxj1 ) relative to most of the other cell lines. P53-flox and P53/BRCA1-flox cells express lower levels of mRNA for epithelial markers ( Cdh1 and Krt19 ) and elevated levels of secretory cell markers ( Ovgp1 ). Pax8 mRNA is equally expressed in all OVE clonal cells, whereas Pax2 is highly expressed in the BRCA1-C1-flox cells. Analyses were performed using multiple t -test analyses for three independent experiments. * p < 0.01, ** p < 0.001, and **** p < 0.00001.
    Figure Legend Snippet: OVE clonal cells have different cell morphology and gene expressions. ( A ) Microphotographs of OVE clonal cells show the epithelial morphology of BRCA1-C2-flox cells and the more mesenchymal morphology of the other three cell lines. Scale bar: 100 μm. ( B ) qPCR analysis shows variable gene expression for epithelial markers ( Cdh1 and Krt19 ), tumor suppressor genes ( Trp53 and Brca1 ), and OVE markers ( Ovgp1, Foxj1, Pax2, and Pax8 ) among the four cell lines. In line with their morphology, BRCA1-C2-flox clonal cells express higher levels of transcripts for epithelial markers ( Cdh1 and Krt19 ) and markers of ciliated cells ( Foxj1 ) relative to most of the other cell lines. P53-flox and P53/BRCA1-flox cells express lower levels of mRNA for epithelial markers ( Cdh1 and Krt19 ) and elevated levels of secretory cell markers ( Ovgp1 ). Pax8 mRNA is equally expressed in all OVE clonal cells, whereas Pax2 is highly expressed in the BRCA1-C1-flox cells. Analyses were performed using multiple t -test analyses for three independent experiments. * p < 0.01, ** p < 0.001, and **** p < 0.00001.

    Techniques Used: Gene Expression



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    Image Search Results


    OVE clonal cells have different cell morphology and gene expressions. ( A ) Microphotographs of OVE clonal cells show the epithelial morphology of BRCA1-C2-flox cells and the more mesenchymal morphology of the other three cell lines. Scale bar: 100 μm. ( B ) qPCR analysis shows variable gene expression for epithelial markers ( Cdh1 and Krt19 ), tumor suppressor genes ( Trp53 and Brca1 ), and OVE markers ( Ovgp1, Foxj1, Pax2, and Pax8 ) among the four cell lines. In line with their morphology, BRCA1-C2-flox clonal cells express higher levels of transcripts for epithelial markers ( Cdh1 and Krt19 ) and markers of ciliated cells ( Foxj1 ) relative to most of the other cell lines. P53-flox and P53/BRCA1-flox cells express lower levels of mRNA for epithelial markers ( Cdh1 and Krt19 ) and elevated levels of secretory cell markers ( Ovgp1 ). Pax8 mRNA is equally expressed in all OVE clonal cells, whereas Pax2 is highly expressed in the BRCA1-C1-flox cells. Analyses were performed using multiple t -test analyses for three independent experiments. * p < 0.01, ** p < 0.001, and **** p < 0.00001.

    Journal: Cancers

    Article Title: P53 Mutation Induces Epithelial-to-Mesenchymal Transition (EMT) Associated with Stem Cell Properties and Tumorigenesis in Fallopian Tube Cells

    doi: 10.3390/cancers17203317

    Figure Lengend Snippet: OVE clonal cells have different cell morphology and gene expressions. ( A ) Microphotographs of OVE clonal cells show the epithelial morphology of BRCA1-C2-flox cells and the more mesenchymal morphology of the other three cell lines. Scale bar: 100 μm. ( B ) qPCR analysis shows variable gene expression for epithelial markers ( Cdh1 and Krt19 ), tumor suppressor genes ( Trp53 and Brca1 ), and OVE markers ( Ovgp1, Foxj1, Pax2, and Pax8 ) among the four cell lines. In line with their morphology, BRCA1-C2-flox clonal cells express higher levels of transcripts for epithelial markers ( Cdh1 and Krt19 ) and markers of ciliated cells ( Foxj1 ) relative to most of the other cell lines. P53-flox and P53/BRCA1-flox cells express lower levels of mRNA for epithelial markers ( Cdh1 and Krt19 ) and elevated levels of secretory cell markers ( Ovgp1 ). Pax8 mRNA is equally expressed in all OVE clonal cells, whereas Pax2 is highly expressed in the BRCA1-C1-flox cells. Analyses were performed using multiple t -test analyses for three independent experiments. * p < 0.01, ** p < 0.001, and **** p < 0.00001.

    Article Snippet: Proteins transferred to nitrocellulose membranes were incubated with primary antibodies against PAX2 (mouse, 1:20,000; Santa Cruz Biotechnology, Dallas, TX, USA), P53 (mouse, 1:10,000; Invitrogen, Thermo Fisher Scientific, Waltham, MA, USA), or BRCA1 (rabbit, 1:200; Santa Cruz Biotechnology, Dallas, TX, USA).

    Techniques: Gene Expression